Rabbit Anti-ALDH1A2 Recombinant Antibody (clone R07-7E3) (CAT#: VS3-XY3257)

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat ALDH1A2

• Species Reactivity
• Human, Mouse, Rat

• Clone
• R07-7E3

• Applications
• WB

• Related Disease
• Diaphragmatic Hernia 4; Neural Tube Defects

• Clonality
• Monoclonal

• Aggregation
• < 5%

• Format
• Liquid

• Buffer
• PBS (pH 7.4), 150 mM NaCl and 50% glycerol

• Preservative
• 0.02% sodium azide

• Storage
• Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• WB: 1/500-1/1000

• Alternative Names
• DIH4; RALDH2; RALDH2-T; RALDH(II)

• Gene ID
• 8854

• UniProt ID
• O94788

• Long Name
• Aldehyde dehydrogenase 1 family member A2

• Cellular Localization
• Cytoplasm

• Post Translation Modifications
• Ubiquitination at Lys108, Lys156, Lys269, Lys290, Lys370, Lys384, Lys390, Lys395, Lys415, and Lys429 (NX_O94788 [NX_O94788-1])
  Modification sites at PhosphoSitePlus (O94788)
  Glycosylation from GlyGen (O94788) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_003879.2; NP_001193826.1

• Function
• Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively.
  Retinoate signaling is critical for the transcriptional control of many genes, for instance it is crucial for initiation of meiosis in both male and female.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

Secondary Antibody

• 2RD-A1473-YJ
• Goat Anti-Rabbit IgG-F(ab')2 Secondary antibody

Select a product category from the dropdown menu below to view related products.