Rabbit Anti-ALDH1A2 Recombinant Antibody (clone R07-7E3)

CAT#: VS3-XY3257

The product is a recombinant rabbit antibody specific for ALDH1A2 (Aldehyde dehydrogenase 1 family member A2), which catalyzes the NAD-dependent oxidation of aldehyde substrates. It recognizes human ALDH1A2 and it also has cross reactivity against mouse or rat ALDH1A2. This product has been reported for use in Western Blot and other applications.

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat ALDH1A2
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R07-7E3
  • Applications
  • WB
  • Related Disease
  • Diaphragmatic Hernia 4; Neural Tube Defects

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000

Target

  • Alternative Names
  • DIH4; RALDH2; RALDH2-T; RALDH(II)
  • Long Name
  • Aldehyde dehydrogenase 1 family member A2
  • Cellular Localization
  • Cytoplasm
  • Post Translation Modifications
  • Ubiquitination at Lys108, Lys156, Lys269, Lys290, Lys370, Lys384, Lys390, Lys395, Lys415, and Lys429 (NX_O94788 [NX_O94788-1])
    Modification sites at PhosphoSitePlus (O94788)
    Glycosylation from GlyGen (O94788) 1 site, 1 O-linked glycan (1 site)
  • Function
  • Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively.
    Retinoate signaling is critical for the transcriptional control of many genes, for instance it is crucial for initiation of meiosis in both male and female.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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