AbPlus™ Anti-APOBEC3B Magnetic Beads (VS-0724-YC1083) (CAT#: VS-0724-YC1083)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-APOBEC3B specific antibody

• Target
• APOBEC3B

• Immunogen
• Synthetic peptide corresponding to the N-terminus of the human APOBEC3B.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]

• Alternative Names
• Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3B; Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B; Phorbolin-1-Related Protein; Phorbolin-2/3; Phorbolin 3; A3B; Probable DNA DC->DU-Editing Enzyme APOBEC-3B; DNA DC->DU-Editing Enzyme APOBEC-3B; Cytidine Deaminase; Phorbolin 2;

• Gene ID
• 9582

• UniProt ID
• Q9UH17

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