AbPlus™ Anti-ASGR1 Magnetic Beads (VS-0724-YC1012)

CAT#: VS-0724-YC1012

The AbPlus Anti-ASGR1 Magnetic Beads (VS-0724-YC1012) is an innovative affinity resin which is bound with anti- ASGR1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ASGR1 protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line Hep G2 Figure 2 Liver Figure 3 RNA cell line category: Cell line enriched (Hep G2)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-ASGR1 specific antibody
  • Target
  • ASGR1
  • Immunogen
  • Recombinant human ASGPR1, aa 62-291.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit.
  • Alternative Names
  • HL-1; ASGPR; ASGPR1; CLEC4H1
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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