AbPlus™ Anti-ATP1A1 Magnetic Beads (M7-PB-E9) (CAT#: VS-0424-XY25)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-ATP1A1 specific antibody (M7-PB-E9)

• Target
• ATP1A1

• Immunogen
• Purified alpha sodium/potassium ATPase from sheep kidney

• Target Species
• Human, Mouse, Chicken, Dog, Pig, Rat, Rabbit, Sheep, Bovine

• Antibody Clone
• M7-PB-E9

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

• Alternative Names
• ATP1A1; ATPase Na+/K+ transporting subunit alpha 1; ATPase; Na+/K+ transporting; alpha 1 polypeptide; ATP1A1

• Gene ID
• 443381

• UniProt ID
• P04074

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