Rabbit Anti-AZI2 Recombinant Antibody (clone R01-7E7) (CAT#: VS3-FY1661)
Clone R01-7E7 is a rabbit IgG recombinant monoclonal antibody that is designed to target human AZI2 protein, a calculated weight of 45 kDa. It cross-reacts with rat.
The following recommendations serve as a starting point for assay optimization. The actual working concentration may vary and should be determined by the user. The R01-7E7 is recommended for detection of target protein by western blotting (dilution range 1:500-1:1000).
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Specifications
- Immunogen
- Recombinant human AZI2 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat AZI2
- Species Reactivity
- Human, Rat
- Clone
- R01-7E7
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 45 kDa, while the observed molecular weight stands at 45 kDa.
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- 5-Azacytidine Induced 2; NF-Kappa-B-Activating Kinase-Associated Protein 1; NAP1; TILP; 5-Azacytidine-Induced Protein 2; 5-Azacytidine Induced Gene 2
- Gene ID
- 64343
- UniProt ID
- Q9H6S1
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- Ubiquitinated via 'Lys-48'-linked polyubiquitination by TRIM38, leading to its degradation.
- Protein Refseq
- XP_005265449.1; XP_047304674.1; XP_011532311.1; XP_011532313.1; XP_011532312.1
- Function
- Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity.
Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization.
Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1.
Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B.
Participates in IFNB promoter activation via TICAM1.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
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