DrugMonitor™ Anti-Belimumab Antibody (VS-1224-YC177)

CAT#: VS-1224-YC177

Belimumab is a fully human recombinant IgG1 lambda monoclonal antibody inhibiting soluble human BLyS, first approved for systemic lupus erythematosus (SLE) and lupus nephritis treatment. The DrugMonitor™ Anti-Belimumab Antibody (VS-1224-YC177) is an anti-drug antibody (ADA) against Belimumab. This drug-based antibody is raised in mice immunized with the Belimumab. The anti-Belimumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Belimumab in samples.

Specifications

  • Host Animal
  • Mouse
  • Specificity
  • Belimumab
  • Target
  • Belimumab
  • Immunogen
  • Belimumab
  • Type
  • Mouse IgG
  • Species Reactivity
  • Human
  • Purity
  • >95%
  • Purification
  • Protein G
  • Applications
  • ELISA, PK/PD, ADA control
  • Format
  • Liquid
  • Concentration
  • Batch-dependent
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
  • Generic name
  • Belimumab
  • Drug Weight
  • 147000.0 Da
  • Formula
  • C₆₃₅₈H₉₉₀₄N₁₇₂₈O₂₀₁₀S₄₄
  • Related Disease
  • Systemic lupus erythematosus (SLE) and lupus nephritis treatment
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Afuco™ Anti-TNFSF13B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-030)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human BLyS. It is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), also known as B-lymphocyte stimulator (BLyS). B cells are responsible for part of the normal immune response, and also for the over-aggressive immune response in autoimmune diseases like systemic lupus erythematosus (SLE).
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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