AbPlus™ Anti-CA8 Magnetic Beads (VS-0724-YC1459)

CAT#: VS-0724-YC1459

The AbPlus Anti-CA8 Magnetic Beads (VS-0724-YC1459) is an innovative affinity resin which is bound with anti-CA8 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CA8 protein under native and denaturing conditions.

Gene Expression
Figure 1 Cerebellum Figure 2 RNA cell line category: Cell line enhanced (HEK93, JURKAT, K-562, NB-4, OE19)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-CA8 specific antibody
  • Target
  • CA8
  • Immunogen
  • Recombinant human Carbonic Anhydrase VIII/CA8, aa 1-290.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3).
  • Alternative Names
  • CALS; CARP; CA-RP; CAMRQ3; CA-VIII
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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