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CA8

Anti-CA8 Products
- Recombinant Mouse Anti-Human CA8 Antibody (MOB-1960MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- AbPlus™ Anti-CA8 Magnetic Beads (VS-0724-YC1459) (VS-0724-YC1459)
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- Target: CA8
- Target Species: Human
- Application: IP, Protein Purification
- Anti-CA8 Immunohistochemistry Kit (VS-0525-XY909)
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- Species Reactivity: Human
- Target: CA8
- Application: IHC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: WB, IP
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3).
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Astrocytes, Gastric mucus-secreting cells, Enteroendocrine cells)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enhanced (HEK93, JURKAT, K-562, NB-4, OE19)
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