DrugMonitor™ Anti-Canakinumab Antibody (VS-1224-YC249)
CAT#: VS-1224-YC249
Canakinumab is a recombinant anti-human IL-1β monoclonal antibody marketed for treating Familial Cold Autoinflammatory Syndrome (FCAS) and Muckle-Wells Syndrome (MWS). The DrugMonitor™ Anti-Canakinumab Antibody (VS-1224-YC249) is an anti-drug antibody (ADA) against Canakinumab. This drug-based antibody is raised in mice immunized with the Canakinumab. The anti-Canakinumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Canakinumab in samples.
Specifications
- Host Animal
- Mouse
- Specificity
- Canakinumab
- Target
- Canakinumab
- Immunogen
- Canakinumab
- Type
- Mouse IgG
- Species Reactivity
- Human
- Purity
- >95%
- Purification
- Protein G
- Applications
- ELISA, PK/PD, ADA control
- Format
- Liquid
- Concentration
- Batch-dependent
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
- Generic name
- Canakinumab
- Drug Weight
- 145157.0 Da (deglycosylated)
- Formula
- C₆₄₅₂H₉₉₅₈N₁₇₂₂O₂₀₁₀S₄₂
- Related Disease
- Familial Cold Autoinflammatory Syndrome (FCAS) and Muckle-Wells Syndrome (MWS)
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See other products for "Canakinumab"
Anti-Human IL1Beta Recombinant Antibody (Canakinumab)Recombinant monoclonal antibody to Human IL1 beta. Canakinumab is a human monoclonal antibody targeted at interleukin-1 beta. It has no cross-reactivity with other members of the interleukin-1 family, including interleukin-1 alpha.
Canakinumab was for the treatment of rheumatoid arthritis. Canakinumab is as a possible treatment for chronic obstructive pulmonary disease, gout and coronary artery disease.
Afuco™ Anti-IL1B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-021)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human IL1 beta. It is a human monoclonal antibody targeted at interleukin-1 beta. It has no cross-reactivity with other members of the interleukin-1 family, including interleukin-1 alpha.
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