Recombinant Anti-CD16 Biparatopic Antibody, Tandem scFv (Clone DJ130c x Clone B88-9)
CAT#: VS-0525-YC26
The recombinant Anti-CD16 biparatopic antibody, tandem scFv (Clone DJ130c x Clone B88-9), targets two distinct domains of CD16. This antibody consists of a tandem scFv, with the DJ130c scFv targeting the initial membrane-distal domain, and is N-terminally linked to the B88-9 scFv, which engages a discontinuous epitope, including LEKDSVTK (aa 21-27), SWKNTALH (aa 113-120), FHHNS (aa 134-138), and VGSKN (aa 158-162).
Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- Human CD16a and CD16b
- Species Reactivity
- Human
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- DJ130c
- Clone 2
- B88-9
- Epitope 1
- The first membrane-distal domain
- Epitope 2
- LEKDSVTK (aa 21-27), SWKNTALH (aa 113-120), FHHNS (aa 134-138) and VGSKN (aa 158-162)
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- FC, IP
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- CD16 Molecule
Target
- Introduction
- CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophils, monocytes, macrophages, and certain T cells. D16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction. The most well-researched membrane receptor implicated in triggering lysis by NK cells, CD16 is a molecule of the immunoglobulin superfamily (IgSF) involved in antibody-dependent cellular cytotoxicity (ADCC). It can be used to isolate populations of specific immune cells through fluorescent-activated cell sorting (FACS) or magnetic-activated cell sorting, using antibodies directed towards CD16.
- Alternative Names
- CD16; CD16A; CD16B; FCG3; FCGR3; FCGR3A; FCGR3B; FCGRIII; FCR-10; FCRIII; FCRIIIA; FCRIIIb; IGFR3; IMD20
- UniProt ID
- P08637
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4015 | Hi-Affi™ Rabbit Anti-CD16 Recombinant Antibody (clone SI78DS) | FC | Rabbit IgG |
| MOR-4016 | Hi-Affi™ Rabbit Anti-CD16 Recombinant Antibody (clone SI79DS) | FC | Rabbit IgG |
| MOR-4017 | Hi-Affi™ Rabbit Anti-CD16 Recombinant Antibody (clone SI80DS) | FC | Rabbit IgG |
| MOR-4018 | Hi-Affi™ Rabbit Anti-CD16 Recombinant Antibody (clone SI81DS) | WB, ELISA | Rabbit IgG |
| MOR-4019 | Hi-Affi™ Rabbit Anti-CD16 Recombinant Antibody (clone SI82DS) | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-258CQ | Mouse Anti-CD16 Recombinant Antibody (clone CBL-1351) | FC, FuncS | Mouse IgG1, κ |
| FAMAB-1632CQ | Human Anti-CD16 Recombinant Antibody (clone DJ130c) | IP, WB, FC, IHC | Human IgG1 |
| FAMAB-1633CQ | Human Anti-CD16 Recombinant Antibody (clone B88-9) | IP, FC, IF | Human IgG1 |
| FAMAB-1737CQ | Rat Anti-CD16 Recombinant Antibody (clone YFC 120.5) | FC | Rat IgG2b |
| ZG-0083J | Mouse Anti-CD16 Recombinant Antibody (clone Q32) | WB, IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0697-YJ-VHH | Camelid Anti-CD16 Recombinant Antibody (HPAB-0697-YJ-VHH) | ELISA, FC | Camelid VHH |
| NBD-0014-YJ-VHH | Camelid Anti-CD16 Recombinant Single Domain Antibody (NBD-0014-YJ-VHH) | ELISA, FuncS | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY61 | Human Anti-CD16 (clone B88-9) scFv-Fc Chimera | IP, FC, IF | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY353 | Anti-CD16 Immunohistochemistry Kit | IHC |
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