AbPlus™ Anti-CEBPA Magnetic Beads (VS-0724-YC401)

CAT#: VS-0724-YC401

The AbPlus Anti-CEBPA Magnetic Beads (VS-0724-YC401) is an innovative affinity resin which is bound with anti-CEBPA specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CEBPA protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line CACO-2 Figure 2 IF staining of human cell line Hep G2 Figure 3 IHC staining of human stomach Figure 4 Pancreas Figure 5 Kidney Figure 6 RNA cell line category: Cell line enhanced (BEWO, Hep G2, NB-4, THP-1, U-937)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-CEBPA specific antibody
  • Target
  • CEBPA
  • Immunogen
  • Synthetic peptide corresponding to the C-terminus of the human CEBPA.
  • Target Species
  • Human, Mouse, Rat
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]
  • Alternative Names
  • CCAAT/Enhancer Binding Protein Alpha; CCAAT/Enhancer Binding Protein (C/EBP), Alpha; CEBP; CCAAT/Enhancer-Binding Protein Alpha; C/EBP-Alpha; C/EBP Alpha;
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