AbPlus™ Anti-CGA Magnetic Beads (1001.1E5.E8) (CAT#: VS-0424-XY63)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-CGA specific antibody (1001.1E5.E8)

• Target
• CGA

• Immunogen
• Native CGA antigen

• Target Species
• Human

• Antibody Clone
• 1001.1E5.E8

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimotos thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

• Alternative Names
• CGA; glycoprotein hormones, alpha polypeptide; glycoprotein hormones alpha chain; chorionic gonadotropin; alpha polypeptide; follicle stimulating hormone alpha subunit; FSHA; GPHa; GPHA1; HCG; LHA; luteinizing hormone alpha chain; lutropin alpha chain

• Gene ID
• 7252

• UniProt ID
• P01222

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