AbPlus™ Anti-CKMT1A Magnetic Beads (VS-0724-YC226)
CAT#: VS-0724-YC226
The AbPlus Anti-CKMT1A Magnetic Beads (VS-0724-YC226) is an innovative affinity resin which is bound with anti-CKMT1A specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CKMT1A protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43491/103202_B_8_5.jpg
Normal Tissue
Figure 2 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43491/103202_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43491/103202_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43491/103202_A_4_6.jpg
Normal Tissue
Figure 5 Skin
Fibroblasts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Keratinocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Langerhans Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43491/103202_B_8_1.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HaCaT, hTCEpi, OE19, SK-BR-3, T-47d)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000223572-CKMT1A
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-CKMT1A specific antibody
- Target
- CKMT1A
- Immunogen
- Recombinant human CKMT1A fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
- Alternative Names
- Creatine Kinase, Mitochondrial 1A; Creatine Kinase, Mitochondrial 1 (Ubiquitous); Acidic-Type Mitochondrial Creatine Kinase; Ubiquitous Mitochondrial Creatine Kinase; EC 2.7.3.2; Mia-CK; U-MtCK;
- Gene ID
- 548596
- UniProt ID
- P12532
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "CKMT1A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0429F | Mouse Anti-CKMT1A Recombinant Antibody (ZG-0429F) | WB | Mouse IgG |
| ZG-0497F | Mouse Anti-CKMT1A Recombinant Antibody (ZG-0497F) | WB | Mouse IgG |
| VS4-WK109 | Mouse Anti-CKMT1A Recombinant Antibody (VS4-WK109) | ELISA, WB | Mouse IgG1 |
| VS7-HM746 | Mouse Anti-CKMT1A Recombinant Antibody (clone CBL166HM) | WB | Mouse IgG |
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