Human Anti-CLDN3 Antibody (CDN28), CHO Stable Cell Pool

Name: Human Anti-CLDN3 Antibody (CDN28), CHO Stable Cell Pool
SKU: VS-1025-QX149
Rating: 5 (1 reviews)

CAT#: VS-1025-QX149

This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant CDN28. CDN28 is a Human monoclonal antibody that targets CLDN3. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of CDN28 into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line MCF7

Immunofluorescent staining of human cell line MCF7 shows localization to cell junctions.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/1661_D5_4_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Endothelial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_B_8_5.jpg

Normal Tissue Figure 3 Small intestine

Endocrine cells
Staining:High
Intensity: Strong
Enterocytes
Staining:High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining:High
Intensity: Strong
Goblet cells
Staining:High
Intensity: Strong
Quantity:>75%
Paneth cells
Staining:High
Intensity: Strong

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_4_2.jpg

Normal Tissue Figure 4 Colon

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_7_3.jpg

Normal Tissue Figure 5 Liver

Cholangiocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_8_4.jpg

Normal Tissue Figure 6 Kidney

Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Collecting ducts
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:High
Intensity: Strong
Quantity:>75%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14361/33701_A_9_5.jpg

RNA Expression Figure 7 RNA cell line category: Cell line enhanced (MCF7, PC-3, RPMI-8226, SCLC-21H, T-47d)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000165215-CLDN3

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Specifications

Host Cell
CHO

Product Type
Stable Cell Pool

Cell Viability
>90%

Mycoplasma Detection
Negative

Bacteria Detection
Negative

Growth Properties
Suspension

Culture Medium
VersaCHO™ Medium (VS-1025-QX582)

Complete Growth Medium
VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)

Freeze Medium
90% VersaCHO™ Medium, 10% DMSO

Growth Conditions
37°C, 5% CO₂

Size
Each vial contains at least 1×10^6 cells in 1 mL

Shipping
Dry ice

Storage
Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.

Antibody Overview

Host Species
Human

Antibody Type
Human IgG1, κ

Clone
CDN28

Target
CLDN3

Species Reactivity
Human

Target

Alternative Names
RVP1; HRVP1; C7orf1; CPE-R2; CPETR2; CLDN3

Gene ID
1365

UniProt ID
O15551

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Downloadable Resources

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Datasheet

Datasheet - VS-1025-QX149.pdf

MSDS

MSDS - VS-1025-QX149.pdf

COA

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