AbPlus™ Anti-CRADD Magnetic Beads (VS-0724-YC225)
CAT#: VS-0724-YC225
The AbPlus Anti-CRADD Magnetic Beads (VS-0724-YC225) is an innovative affinity resin which is bound with anti-CRADD specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of CRADD protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5337/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5337/19087_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5337/19087_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5337/19087_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5337/19087_A_6_6.jpg
Normal Tissue
Figure 6 Heart muscle
Cardiomyocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5337/19087_B_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169372-CRADD
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-CRADD specific antibody
- Target
- CRADD
- Immunogen
- Recombinant human CRADD/RAIDD, aa 1-199.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- CRADD (CASP2 And RIPK1 Domain Containing Adaptor With Death Domain) is a Protein Coding gene. Diseases associated with CRADD include Mental Retardation, Autosomal Recessive 34, With Variant Lissencephaly and Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Apoptosis Modulation and Signaling and Apoptosis and survival Caspase cascade. Gene Ontology (GO) annotations related to this gene include protease binding and death domain binding.
- Alternative Names
- CASP2 And RIPK1 Domain Containing Adaptor With Death Domain; RIP-Associated ICH1/CED3-Homologous Protein With Death Domain; RAIDD; RIP-Associated Protein With A Death Domain; Caspase And RIP Adaptor With Death Domain; Caspase And RIP Adapter With Death Domain;
- Gene ID
- 8738
- UniProt ID
- P78560
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CRADD"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1766CT | Recombinant Mouse anti-Human CRADD Monoclonal antibody (EML2017) | WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0798 | Hi-Affi™ Rabbit Anti-CRADD Recombinant Antibody (clone DS798AB) | FC, ICC, IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY536 | Anti-CRADD Immunohistochemistry Kit | IHC | |
| VS-0525-XY1657 | Anti-Human CRADD Immunohistochemistry Kit | IHC |
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