Mouse Anti-CRY2 Recombinant Antibody (VS3-FY2676)
CAT#: VS3-FY2676
This anti-CRY2 antibody is a mouse recombinant monoclonal antibody that is specifically engineered to target Cry2. The calculated molecular weight of the antigen is 66.9 kDa. It exhibits cross-reactivity with human, mouse and rat. This monoclonal antibody is potential for conducting research on Advanced Sleep Phase Syndrome and Delayed Sleep Phase Disorder. The antibody can be utilized for detection of CRY2 by Western Blot.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Cryptochrome circadian regulator 2 of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 66.9 kDa.
- Related Disease
- Advanced Sleep Phase Syndrome and Delayed Sleep Phase Disorder
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Target
- Alternative Names
- Cryptochrome Circadian Regulator 2; Cryptochrome 2 (Photolyase-Like); Cryptochrome Circadian Clock 2; Growth-Inhibiting Protein 37; Cryptochrome-2; KIAA0658; HCRY2; PHLL2
- Gene ID
- 1408
- UniProt ID
- Q49AN0
- Sequence Similarities
- Belongs to the DNA photolyase class-1 family.
- Cellular Localization
- Cytoplasm
Nucleus
- Post Translation Modifications
- Phosphorylation on Ser-266 by MAPK is important for the inhibition of CLOCK-BMAL1-mediated transcriptional activity.
Ubiquitinated by the SCF(FBXL3) and SCF(FBXL21) complexes, regulating the balance between degradation and stabilization.
Ubiquitination at Lys30, Lys126, Lys242, Lys348, Lys475, and Lys504
Modification sites at PhosphoSitePlus
- Protein Refseq
- NP_001120929.1; NP_066940.3
- Function
- Plays a key role in glucose and lipid metabolism modulation, in part, through the transcriptional regulation of genes involved in these pathways, such as LEP or ACSL4.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "CRY2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1026 | Mouse Anti-CRY2 Recombinant Antibody (VS3-WK1026) | WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY554 | Anti-CRY2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1687 | Anti-Mouse CRY2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1686 | Anti-Human CRY2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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