Chicken Anti-CTX Recombinant Antibody (clone 2S7) (CAT#: VS-0323-CJ11)
This chicken anti-CTX antibody (clone 2S7) is a product that recognizes NNA venom Cytotoxin (CTX).
Specific Inquiry
ELISA
Figure 1 The ability of the two scFvs (VS-0323-CJ10 and VS-0323-CJ11) to bind to CTX was evaluated by indirect ELISA.
Specifications
- Immunogen
- Attenuated CTX
- Host Species
- Chicken
- Type
- Chicken IgY
- Specificity
- NNA venom Cytotoxin (CTX)
- Species Reactivity
- NNA
- Clone
- 2S7
- Applications
- Enzyme-linked Immunosorbent Assay, Western Blot
- Conjugate
- Unconjugated
- Related Disease
- Snakebite
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cytotoxin
- UniProt ID
- P60304
- Sequence Similarities
- Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
- Cellular Localization
- Membrane; Secreted; Target cell membrane; Target membrane
- Function
- Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. Interaction with sulfatides in the cell membrane induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It targets the mitochondrial membrane and induces mitochondrial swelling and fragmentation (By similarity).
It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity and inhibits protein kinases C (PubMed:8448165).
It also binds with high affinity to heparin (PubMed:17685633).
It also causes skeletal muscle necrosis after intramuscular injection into mice (PubMed:8342169).
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CTX"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-056 | Mouse Anti-CTX Recombinant Antibody (clone TE33) | ELISA, WB, FuncS | Mouse IgG |
| FAMAB-0142WJ | Camelid Anti-CTX Recombinant Antibody (clone LCTA9) | ELISA, Neut | Camelid VHH |
| FAMAB-0143WJ | Camelid Anti-CTX Recombinant Antibody (clone LCTC11) | ELISA, Neut | Camelid VHH |
| FAMAB-0144WJ | Camelid Anti-CTX Recombinant Antibody (clone LCTG3) | ELISA, Neut | Camelid VHH |
| FAMAB-0145WJ | Camelid Anti-CTX Recombinant Antibody (clone LCTG4) | ELISA, Neut | Camelid VHH |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-056 | Mouse Anti-CTX Recombinant Antibody (clone TE33); scFv Fragment | ELISA, WB, FuncS | Mouse scFv |
| FAMAB-0078-YC-S(P) | Recombinant Human Anti-CTX Antibody scFv Fragment (sc1) | ELISA | Human scFv |
| FAMAB-0079-YC-S(P) | Recombinant Human Anti-CTX Antibody scFv Fragment (sc8) | ELISA | Human scFv |
| FAMAB-0080-YC-S(P) | Recombinant Human Anti-CTX Antibody scFv Fragment (sc6) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-056 | Mouse Anti-CTX Recombinant Antibody (clone TE33); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
| FAMAB-0078-YC-F(E) | Recombinant Human Anti-CTX Antibody Fab Fragment (sc1) | ELISA | Human Fab |
| FAMAB-0079-YC-F(E) | Recombinant Human Anti-CTX Antibody Fab Fragment (sc8) | ELISA | Human Fab |
| FAMAB-0080-YC-F(E) | Recombinant Human Anti-CTX Antibody Fab Fragment (sc6) | ELISA | Human Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-033 | Recombinant Anti-cholera CTX VHH Single Domain Antibody (A9) | Inhib, FuncS | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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