CytoStream™ Rabbit Anti-CYP1B1 Recombinant Antibody (VS13-YC281) (CAT#: VS13-YC281)
The CytoStream™ Rabbit Anti-CYP1B1 Recombinant Antibody is specific for human, mouse and rat CYP1B1. CYP1B1, another cytochrome P450 family member, plays a role in metabolizing estrogen, associated with primary congenital glaucoma and earlier segment dysgenesis, impacting pathways like the aryl hydrocarbon receptor. The anti-CYP1B1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/if_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/if_selected.jpg
Figure 2 IHC staining of human skeletal muscle
(Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/61863_B_3_6_selected.jpg
(Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/61863_B_3_6_selected.jpg
Figure 3 IHC staining of human gall bladder
(Immunohistochemical staining of human gall bladder shows moderate cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11705/ihc_selected.jpg
(Immunohistochemical staining of human gall bladder shows moderate cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11705/ihc_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/61863_B_7_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/61863_B_7_5.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/61863_A_8_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/61863_A_8_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/61863_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26863/61863_A_4_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HSkMC, hTERT-RPE1, SiHa, U-87 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000138061-CYP1B1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000138061-CYP1B1
Specifications
- Immunogen
- Recombinant human CYP1B1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat CYP1B1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, FC
- Conjugate
- NONE
- Related Disease
- Glaucoma, Primary Congenital, A and Anterior Segment Dysgenesis
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Cytochrome P450 Family 1 Subfamily B Member 1; Cytochrome P450, Subfamily I (Dioxin-Inducible), Polypeptide 1 (Glaucoma 3, Primary Infantile); Cytochrome P450, Family 1, Subfamily B, Polypeptide 1; EC 1.14.14.1; CYPIB1; Flavoprotein-Linked Monooxygenase; Aryl Hydrocarbon Hydroxylase; Microsomal Monooxygenase;
- Gene ID
- 1545
- UniProt ID
- Q16678
- Long Name
- Cytochrome P450 Family 1 Subfamily B Member 1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2342z | Mouse Anti-CYP1B1 Recombinant Antibody (clone 28G6) | WB, ELISA, IHC | Mouse IgG1, κ |
| VS3-FY437 | Recombinant Rabbit Anti-CYP1B1 Antibody (clone R02-5A3) | WB, IHC-P | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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