Mouse Anti-DENV prM Recombinant Antibody (clone prM12)

CAT#: VS-0326-FY56

The antibody is a potent tool for studying flavivirus maturation and pathogenesis. It specifically target a conserved immunodominant epitope on the dengue virus premembrane (prM) protein, primarily residues K26 and E28.

Specifications

  • Immunogen
  • Infection with DENV2 strain New Guinea C followed by boosting with recombinant pr protein (residues 1-86 of prM).
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2
  • Antibody Isotype
  • IgG2
  • Specificity
  • Cross-reactive against multiple DENV serotypes (DENV1-4); No cross-reactivity with Zika virus (ZIKV).
  • Species Reactivity
  • Dengue Virus (DENV)
  • Clone
  • prM12
  • Applications
  • Neutralization, Western Blot, Enzyme-linked Immunosorbent Assay
  • Related Disease
  • Dengue fever

Product Property

  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • prM protein
  • Long Name
  • Dengue Virus Pre-membrane Protein
  • Function
  • Membrane precursor; prevents premature fusion during virus maturation.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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