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    Human Anti-DERL1 Recombinant Antibody (clone hu8D3); scFv Fragment (CAT#: HPAB-AP625-YC-S(P))

    Provided is an humanized antibody of a DERLIN-1 protein which resists surface expression of a cancer cell. The antibody can be used in some immunoassay techniques such as: ELISA.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16562/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human urinary bladder
    Figure 2 IHC staining of human urinary bladder
    (Immunohistochemical staining of human urinary bladder shows distinct cytoplasmic positivity in urothelial cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/16562/ihc_selected.jpg
    Figure 3 Lymph node
    Figure 3 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37269/85416_A_9_8.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37269/85416_B_9_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37269/85416_A_9_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37269/85416_A_9_4.jpg
    Figure 7 Gallbladder
    Figure 7 Gallbladder
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37269/85416_A_5_4.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37269/85416_A_8_5.jpg
    Figure 9 Testis
    Figure 9 Testis
    (Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37269/85416_A_6_6.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (SK-BR-3)
    Figure 10 RNA cell line category: Cell line enhanced (SK-BR-3)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136986-DERL1

    Specifications

    • Host Species
    • Human
    • Derivation
    • Humanized
    • Type
    • Humanized scFv
    • Specificity
    • Human DERL1
    • Species Reactivity
    • Human
    • Clone
    • hu8D3
    • Applications
    • ELISA
    • Related Disease
    • Cancer

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • Derlin 1; Degradation In Endoplasmic Reticulum Protein 1; Der1-Like Domain Family, Member 1; DERtrin-1; DER1; Der1-Like Protein 1; Derlin-1; DER-1

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    Please select product type
    IgG Antibody Products Fab Antibody Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-3301z Mouse Anti-DERL1 Recombinant Antibody (clone 16A12) WB, IP, ELISA Mouse IgG1, κ
    HPAB-AP625-YC Human Anti-DERL1 Recombinant Antibody (clone hu8D3) ELISA Humanized IgG

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