Human Anti-DNA-PKcs Recombinant Antibody (VS-0723-CJ2) (CAT#: VS-0723-CJ2)
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) fragment DPK3 is located between the leucine zipper (LZ) and T2609 autophosphorylation cluster. The scFv format of this antibody enhanced the sensitivity of tumours transplanted in Balb/c athymic mice to radiation therapy. This antibody has been tested for use in western blot, enzyme-linked immunosorbent assay, immunohistochemistry and immunofluorescence.
Specific Inquiry
Specifications
- Immunogen
- Purified DNA-PKcs fragment (DPK3, a.a.1960-2227)
- Host Species
- Human
- Derivation
- Humanized
- Type
- Human IgG
- Specificity
- DNA-dependent protein kinase catalytic subunit (DNA-PKcs)
- Species Reactivity
- Human
- Applications
- ELISA, IB, IHC, IF
- Conjugate
- Unconjugated
- Related Disease
- Tumors
Product Property
- Purification
- Protein A purified
- Purity
- >95%
- Buffer
- PBS
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody were determined by ELISA assay coated with purified DPK3 as antigen. Immunohybridization analysis of total extract of HeLa cells using this antibody showed an unique immunobinding band with DNA-PKcs. This antibody decreases the activity of DNA-PKcs in response to radiation and enhances the sensitivity of tumours to radiotherapy.
Target
- Alternative Names
- DNA-dependent protein kinase catalytic subunit
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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