Mouse Anti-DNA Quadruplex Recombinant Antibody (clone meV-IIB4) (CAT#: FAMAB-0102CQ)
Recombinant Mouse Antibody clone meV-IIB4, which is specific to DNA Quadruplex. The meV IIB4 antibody reported here is the first immunoreagent we are aware of that reacts in a structurally specific manner with quadruplex DNAs. meV IIB4 Antibody Binds Quadruplex DNAs with Higher Affinities Than Triplex and Duplex DNAs.
Specific Inquiry
RIFB
Figure 1 Scatchard plots of RIFB data for quadruplexes binding to the meV-IIB4 antibody.
Binding parameters were derived from linear regression lines of Scatchard plots. (A) TET4; (B) TG4; (C) G4.
Brown, B. A., 2nd, Li, Y., Brown, J. C., Hardin, C. C., Roberts, J. F., Pelsue, S. C., & Shultz, L. D. (1998). Isolation and characterization of a monoclonal anti-quadruplex DNA antibody from autoimmune "viable motheaten" mice. Biochemistry, 37(46), 16325–16337.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgM, κ
- Clone
- meV-IIB4
- Applications
- ELISA
- Related Disease
- Systemic lupus erythematosus (SLE)
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- DNA; Deoxyribonucleic acid; polynucleotides; double heliX
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0102CQ-F(E) | Mouse Anti-DNA Quadruplex Recombinant Antibody (clone meV-IIB4); Fab Fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0102CQ-S(P) | Mouse Anti-DNA Quadruplex Recombinant Antibody (clone meV-IIB4); scFv Fragment | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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