DrugMonitor™ Anti-Durvalumab Antibody (VS-1224-YC381)

CAT#: VS-1224-YC381

Durvalumab is a human IgG1 kappa monoclonal antibody and immune-checkpoint inhibitor approved for use with etoposide and either carboplatin or cisplatin as first-line treatment for extensive-stage small cell lung cancer (ES-SCLC). The DrugMonitor™ Anti-Durvalumab Antibody (VS-1224-YC381) is an anti-drug antibody (ADA) against Durvalumab. This drug-based antibody is raised in mice immunized with the Durvalumab. The anti-Durvalumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Durvalumab in samples.

Specifications

  • Host Animal
  • Mouse
  • Specificity
  • Durvalumab
  • Target
  • Durvalumab
  • Immunogen
  • Durvalumab
  • Type
  • Mouse IgG
  • Species Reactivity
  • Human
  • Purity
  • >95%
  • Purification
  • Protein G
  • Applications
  • ELISA, PK/PD, ADA control
  • Format
  • Liquid
  • Concentration
  • Batch-dependent
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
  • Generic name
  • Durvalumab
  • Drug Weight
  • 146300.0 Da
  • Formula
  • C₆₅₀₂H₁₀₀₁₈N₁₇₄₂O₂₀₂₄S₄₂
  • Related Disease
  • extensive-stage small cell lung cancer (ES-SCLC)
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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