Afuco™ Anti-CD274 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-417CQ) (CAT#: AFC-TAB-417CQ)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD274. It is a human monoclonal antibody that can be potentially used in the treatment of Cancers, non-small cell lung (NSCLC), Solid tumors, bladder, urothelial.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Specificity
  • Human CD274
  • Species Reactivity
  • Human
  • Applications
  • ELISA, IHC, FC, IP, IF, Inhib
  • Conjugate
  • Unconjugated
  • Trade name
  • Imfinzi
  • Generic Name
  • Durvalumab
  • Related Disease
  • Cancers, non-small cell lung (NSCLC), Solid tumors, bladder, urothelial

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Programmed cell death 1 ligand 1; B7H1; B7-H1; PDL1; PD-L1; PDCD1L1; B7 homolog 1; B7 homologue 1

Related Resources

  • Biosimilar Overview
Please refer to Durvalumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Durvalumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Durvalumab"

DrugMonitor™ Anti-Durvalumab Antibody (VS-1224-YC381)
Durvalumab is a human IgG1 kappa monoclonal antibody and immune-checkpoint inhibitor approved for use with etoposide and either carboplatin or cisplatin as first-line treatment for extensive-stage small cell lung cancer (ES-SCLC). The DrugMonitor™ Anti-Durvalumab Antibody (VS-1224-YC381) is an anti-drug antibody (ADA) against Durvalumab. This drug-based antibody is raised in mice immunized with the Durvalumab. The anti-Durvalumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Durvalumab in samples.

See other products for "Cd274"

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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