Human Anti-E1/E2 Protein Recombinant Antibody (clone SKT05)
CAT#: VS-0326-FY8
A premier broadly neutralizing antibody (bnAb) that surmounts alphavirus sequence diversity by recognizing the protein backbone. It targets a conserved region proximal to the E1 fusion peptide. It is uniquely effective as a prophylactic agent against both encephalitic (VEEV) and arthritogenic (CHIKV, RRV) alphaviruses, making it a high-value therapeutic candidate.
Specifications
- Immunogen
- Trivalent VLPs (WEEV, EEEV, VEEV)
- Host Species
- Human
- Type
- Human IgG1
- Antibody Isotype
- IgG1
- Species Reactivity
- Western Equine Encephalitis Virus (WEEV), Eastern Equine Encephalitis Virus (EEEV), Venezuelan Equine Encephalitis Virus (VEEV), Chikungunya Virus (CHIKV), Ross River Virus (RRV), O'nyong-nyong Virus (ONNV), Mayaro Virus (MAYV)
- Clone
- SKT05
- Applications
- Neutralization
- Related Disease
- Hepatitis C, Viral infection
Product Property
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- E1/E2 complex
- Long Name
- Alphavirus Envelope Proteins E1 and E2
- Function
- Envelope glycoproteins; mediate viral attachment and fusion with host cell membranes.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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