Recombinant Anti-EBV LMP1 (AA 242-328 x AA 328-386) Biparatopic Antibody, Tandem scFv (Clone F5 x Clone G5)

CAT#: VS-0525-YC60

Recombinant Anti-EBV LMP1 (AA 242-328 x AA 328-386) Biparatopic Antibody, Tandem scFv (Clone F5 x Clone G5), is a biparatopic antibody (bpAb) engineered to bind two distinct epitopes of EBV LMP1. This bpAb was designed as a tandem scFv, with the F5 scFv (targeting LMP1 AA 242-328) N-terminally fused to the G5 scFv (targeting LMP1 AA 328-386).

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Human
  • Specificity
  • EBV LMP1
  • Species Reactivity
  • EBV
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • F5
  • Clone 2
  • G5
  • Epitope 1
  • aa 242-328
  • Epitope 2
  • aa 328-386
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Epstein-Barr virus Latent Membrane Protein 1

Target

  • Introduction
  • The Epstein-Barr virus (EBV) has been implicated in the development of many human neoplasias including B lymphoma and nasopharyngeal carcinoma. EBV latent membrane protein 1 (LMP1) is essential to virus-induced B cell immortalization and the downregulation of cell adhesion molecules that increases cell motility. Therefore, identifying LMP1 activity modulation methods may lead to the development of new therapies for LMP1-positive tumors.
  • Alternative Names
  • Latent membrane protein 1
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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