Mouse Anti-ECT2 Recombinant Antibody (VS3-FY2694)
CAT#: VS3-FY2694
This anti-ECT2 antibody is a mouse recombinant monoclonal antibody that is specifically created to bind ECT2 protein, a calculated weight of 103.5 kDa. It cross-reacts with human and mouse. This monoclonal antibody is potential for conducting research on Cataract 36 and Squamous Cell Carcinoma. The antibody can be utilized for detection of ECT2 by Western Blot.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Epithelial cell transforming 2 of human and mouse origins
- Species Reactivity
- Human, Mouse
- Applications
- WB
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 103.5 kDa.
- Related Disease
- Cataract 36 and Squamous Cell Carcinoma
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Epithelial Cell Transforming 2; Epithelial Cell-Transforming Sequence 2 Oncogene; Epithelial Cell Transforming Sequence 2 Oncogene; Protein ECT2; ARHGEF31
- Gene ID
- 1894
- UniProt ID
- Q9H8V3
- Cellular Localization
- Nucleus
Cytoplasm
Cytoplasm, cytoskeleton, spindle
Cleavage furrow
Midbody
Cell junction
Cell junction, tight junction
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
- Post Translation Modifications
- Phosphorylated by PLK1 in vitro.
Modification sites at PhosphoSitePlus
Modification sites at neXtProt
Glycosylation from GlyGen 2 sites, 1 O-linked glycan (2 sites)
- Function
- Plays a role in the control of mitotic spindle assembly; regulates the activation of CDC42 in metaphase for the process of spindle fibers attachment to kinetochores before chromosome congression.
Involved in the regulation of epithelial cell polarity; participates in the formation of epithelial tight junctions in a polarity complex PARD3-PARD6-protein kinase PRKCQ-dependent manner.
Plays a role in the regulation of neurite outgrowth.
Inhibits phenobarbital (PB)-induced NR1I3 nuclear translocation.
Stimulates the activity of RAC1 through its association with the oncogenic PARD6A-PRKCI complex in cancer cells, thereby acting to coordinately drive tumor cell proliferation and invasion.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "ECT2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1158 | Mouse Anti-ECT2 Recombinant Antibody (VS3-WK1158) | WB, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2148 | Anti-ECT2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2149 | Anti-Mouse ECT2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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