Edrecolomab is a mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM (17-1A). The DrugMonitor™ Anti-Edrecolomab Antibody (VS-1224-YC392) is an anti-drug antibody (ADA) against Edrecolomab. This drug-based antibody is raised in mice immunized with the Edrecolomab. The anti-Edrecolomab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Edrecolomab in samples.
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Anti-Human EpCAM/17-1A Recombinant Antibody (Edrecolomab)Recombinant mouse monoclonal antibody expressed in Sp2/0 mouse myeloma cells binding to human EpCAM/17-1A. Edrecolomab is a mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM/17-1A, which is expressed on epithelial tissues and on various carcinomas. Preliminary studies had shown promise of a possible use in patients with stage III colorectal carcinoma. However, when put to a phase III study it did not provide any benefit when compared to conventional chemotherapeutic agents. Edrecolomab was well tolerated in these studies and as such research has now concentrated on whether it can be of any use in other forms of cancer.
Afuco™ Anti-EpCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-701)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant mouse monoclonal antibody expressed in Sp2/0 mouse myeloma cells binding to human EpCAM/17-1A. It is a mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM/17-1A, which is expressed on epithelial tissues and on various carcinomas.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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