Mouse Anti-EEEV E2 Vaccinal Antibody (VS-0625-XY14)
CAT#: VS-0625-XY14
Crafted for precise EEEV E2 recognition, this antibody supports ELISA, inhibition, and neutralization studies, demonstrating robust binding to the target. Its Fc engineering drives vaccine-like immune activation, simultaneously augmenting antiviral activity to improve protection against EEEV infection.
Specifications
- Target
- EEEV E2
- Host Animal
- Mouse
- Applications
- ELISA; Inhib; Neut
- Specificity
- EEEV E2
- Immunogen
- SINV-EEEV
- Species Reactivity
- EEEV
- Type
- Mouse IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein G purified
- Epitope
- Epitope in the "wing region" (residues 51-81) on E2
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- EEEV is a mosquito-transmitted alphavirus with a high case mortality rate in humans. EEEV is a biodefense concern because of its potential for aerosol spread and the lack of existing countermeasures. The E2 glycoprotein projects from the viral surface and is comprised of three domains: A, B, and C11,12. Binding of EEEV E2 to poorly characterized host receptors is believed to initiate entry and endocytosis13. The acidic environment of the endosome induces conformational changes in the alphavirus E1 and E2 glycoproteins, which allow for the exposure of the fusion loop, insertion into the host membrane11, and nucleocapsid escape into the cytoplasm.
- Related Disease
- Febrile illness; Neurologic disease
- Alternative Names
- EEEV E2 glycoprotein
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "EEEV E2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1161LC | Anti-EEEV E2 Recombinant Antibody (EEEV-6E2) | ELISA, WB | Mouse Antibody |
| MRO-1161LC-S(P) | Anti-EEEV E2 Recombinant Antibody scFv Fragment (EEEV-6E2) | ELISA, WB | Mouse Antibody |
| MRO-1161LC-F(E) | Anti-EEEV E2 Recombinant Antibody Fab Fragment (EEEV-6E2) | ELISA, WB | Mouse Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0236 | Mouse Anti-EEEV E2 Recombinant Antibody (PABJ-0236) | Neut | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-XY13 | Mouse Anti-EEEV E2 Vaccinal Antibody (VS-0625-XY13) | ELISA, Inhib, Neut | Mouse IgG |
| VS-0625-XY15 | Mouse Anti-EEEV E2 Vaccinal Antibody (VS-0625-XY15) | ELISA, Inhib, Neut | Mouse IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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