AbPlus™ Anti-EIF2AK2 Magnetic Beads (CBACN-453)
CAT#: VS-0424-XY85
The AbPlus Anti-EIF2AK2 Magnetic Beads (CBACN-453) is an innovative affinity resin which is bound with anti-EIF2AK2 specific antibody (CBACN-453). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of EIF2AK2 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/63893/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3845/if_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3845/10337_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3845/10337_A_8_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3845/10337_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3845/10337_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3845/10337_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000055332-EIF2AK2
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-EIF2AK2 specific antibody (CBACN-453)
- Target
- EIF2AK2
- Immunogen
- Human PKR, aa 500-600
- Target Species
- Human
- Antibody Clone
- CBACN-453
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
- Alternative Names
- Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2; Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent; Protein Phosphatase 1, Regulatory Subunit 83; Tyrosine-Protein Kinase EIF2AK2; P1/EIF-2A Protein Kinase; EIF-2A Protein Kinase 2; Protein Kinase R; P68 Kinase; PRKR; PKR; Interferon-Induced, Double-Stranded RNA-Activated Protein Kinase
- Gene ID
- 5610
- UniProt ID
- P19525
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "EIF2AK2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2694z | Mouse Anti-EIF2AK2 Recombinant Antibody (clone 21F8) | WB, ELISA, FC, IHC | Mouse IgG1 |
| MOB-0783MZ | Recombinant Mouse Anti-Human EIF2AK2 Antibody | ICC, IF, WB | Mouse antibody |
| VS3-CJ749 | Mouse Anti-EIF2AK2 Recombinant Antibody (VS3-CJ749) | WB, IF | Mouse IgG1, κ |
| VS3-CJ750 | Rabbit Anti-EIF2AK2 Recombinant Antibody (VS3-CJ750) | WB, ICC, IF, IHC, IP | Rabbit IgG |
| VS3-CJ751 | Rabbit Anti-EIF2AK2 (phospho T446) Recombinant Antibody (VS3-CJ751) | WB, IHC, IP, ChIP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0669MZ | Chicken Anti-EIF2AK2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1114 | Hi-Affi™ Rabbit Anti-EIF2AK2 Recombinant Antibody (clone DS1114AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY739 | Anti-EIF2AK2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2205 | Anti-Human EIF2AK2 Immunohistochemistry Kit | IHC |
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