AbPlus™ Anti-EIF2AK2 Magnetic Beads (CBACN-453) (CAT#: VS-0424-XY85)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-EIF2AK2 specific antibody (CBACN-453)

• Target
• EIF2AK2

• Immunogen
• Human PKR, aa 500-600

• Target Species
• Human

• Antibody Clone
• CBACN-453

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

• Alternative Names
• Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2; Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent; Protein Phosphatase 1, Regulatory Subunit 83; Tyrosine-Protein Kinase EIF2AK2; P1/EIF-2A Protein Kinase; EIF-2A Protein Kinase 2; Protein Kinase R; P68 Kinase; PRKR; PKR; Interferon-Induced, Double-Stranded RNA-Activated Protein Kinase

• Gene ID
• 5610

• UniProt ID
• P19525

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