Rabbit Anti-Helicobacter pylori urease Antibody (VS-0925-XY20)

CAT#: VS-0925-XY20

Helicobacter pylori urease antibodies bind this acid-neutralizing enzyme, useful in ELISA for detection, Western blotting, and neutralization assays to research its role in gastric survival and colonization.

Specifications

  • Host Animal
  • Rabbit
  • Applications
  • ELISA
  • Specificity
  • Helicobacter pylori urease
  • Target
  • Helicobacter pylori urease
  • Species Reactivity
  • Bacteria
  • Type
  • Rabbit IgG
  • Purification
  • Protein A Purified
  • Format
  • Liquid
  • Buffer
  • PBS with 1% BSA, 50% glycerol
  • Preservative
  • 0.09% sodium azide
  • Storage
  • This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.

Target

  • Introduction
  • Helicobacter pylori urease is an enzyme produced by Helicobacter pylori, critical for survival in the acidic gastric environment. It catalyzes the hydrolysis of urea in gastric juice to ammonia and carbon dioxide, neutralizing local gastric acid to create a suitable microenvironment. Urease also aids bacterial adhesion to gastric epithelial cells and triggers host immune responses, contributing to gastric inflammation. It is a key virulence factor, widely used as a marker for Helicobacter pylori infection diagnosis (e.g., urea breath test) and a candidate antigen for vaccines.
  • Alternative Names
  • H. pylori Urease Enzyme, Hp Urease
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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