Rabbit Anti-Mycobacterium tuberculosis Ag85C Antibody (VS-0925-XY37)
CAT#: VS-0925-XY37
Mycobacterium tuberculosis Ag85C antibodies bind this Ag85 family protein, facilitating Western blotting, immunofluorescence, and studies on its unique role in cell wall synthesis. Valuable for dissecting Ag85C's distinct contributions to tuberculosis pathogenesis and vaccine development.
Specifications
- Host Animal
- Rabbit
- Applications
- WB
- Specificity
- Mycobacterium tuberculosis Ag85C
- Target
- Mycobacterium tuberculosis Ag85C
- Immunogen
- Recombinant Mycobacterium tuberculosis Diacylglycerol acyltransferase/mycolyltransferase Ag85C protein
- Species Reactivity
- Bacteria
- Type
- Rabbit IgG
- Purification
- Protein G Purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4, with 50% glycerol
- Preservative
- 0.03% ProClin 300
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Mycobacterium tuberculosis Ag85C is another vital protein in the Ag85 family of Mycobacterium tuberculosis, sharing structural homology with Ag85A and Ag85B but with unique functional nuances. Like other Ag85 members, it contributes to bacterial cell wall synthesis by aiding in mycolic acid cross-linking, which is crucial for the bacterium's survival and resistance to host defenses. Ag85C has distinct immunogenic properties; it can trigger specific immune responses in the host, including the activation of cytotoxic T cells that target infected cells. Its conservation across most Mycobacterium tuberculosis strains makes it a valuable candidate for broad-spectrum tuberculosis vaccines. It also serves as a potential diagnostic marker, as its presence or the host's immune response to it can indicate active tuberculosis infection, complementing other diagnostic tools.
- Alternative Names
- M. tuberculosis Antigen 85C, Mtb Ag85C
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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