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    DrugMonitor™ Anti-Ertumaxomab Antibody (VS-1224-YC447)

    CAT#: VS-1224-YC447

    Ertumaxomab is an intact bispecific antibody targeting HER2/neu and CD3, with preferential binding to activating Fc gamma type I/III-receptors, under investigation for metastatic breast cancer treatment after trastuzumab progression. The DrugMonitor™ Anti-Ertumaxomab Antibody (VS-1224-YC447) is an anti-drug antibody (ADA) against Ertumaxomab. This drug-based antibody is raised in mice immunized with the Ertumaxomab. The anti-Ertumaxomab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Ertumaxomab in samples.

    Specifications

    • Host Animal
    • Mouse
    • Specificity
    • Ertumaxomab
    • Target
    • Ertumaxomab
    • Immunogen
    • Ertumaxomab
    • Type
    • Mouse IgG
    • Purity
    • >95%
    • Purification
    • Protein G
    • Applications
    • ELISA, PK/PD, ADA control
    • Format
    • Liquid
    • Concentration
    • Batch-dependent
    • Buffer
    • PBS, pH 7.4
    • Preservative
    • No preservatives
    • Storage
    • Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
    • Generic name
    • Ertumaxomab
    • Related Disease
    • metastatic breast cancer treatment after trastuzumab progression
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    Datasheet

    Datasheet - VS-1224-YC447.pdf

    MSDS

    MSDS - VS-1224-YC447.pdf

    COA

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    See other products for "ertumaxomab"

    Anti-Human CD3E Recombinant Antibody (Ertumaxomab)
    Recombinant Rat antibody to Human CD3E. Ertumaxomab (trade name Rexomun) is a rat-murine hybrid monoclonal antibody designed to treat some types of cancer. It is a so-called trifunctional antibody which works by linking T-lymphocytes and macrophages to the cancer cells.
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