Rabbit Anti-ESR2 Recombinant Antibody (clone R04-2G5) (CAT#: VS3-XY3350)
This is a recombinant rabbit antibody targeting the human ESR2 (Estrogen receptor 2). It has been reported for use in Western Blot and Immunohistochemistry-Paraffin. The recommended dilutions of western blot and Immunohistochemistry-Paraffin is 1/500-1/1000 and 1/50-1/100, respectively.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68406/1984_B8_27_cr5e5cf7eb9f573_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68406/1984_B8_27_cr5e5cf7eb9f573_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166418_B_9_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166418_B_9_5.jpg
Figure 3 Colon
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_3.jpg
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_9_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_9_4.jpg
Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140009-ESR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140009-ESR2
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human ESR2
- Species Reactivity
- Human
- Clone
- R04-2G5
- Applications
- WB, IHC-P
- Related Disease
- Ovarian Dysgenesis 8; Thyroid Carcinoma, Familial Medullary
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- Erb; ESRB; ODG8; ESTRB; NR3A2; ER-BETA; ESR-BETA
- Gene ID
- 2100
- UniProt ID
- Q92731
- Long Name
- Estrogen receptor 2
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Phosphorylation at Ser-87 and Ser-105 recruits NCOA1. (Q92731-ESR2_HUMAN)
Modification sites at PhosphoSitePlus (Q92731)
Modification sites at neXtProt (NX_Q92731)
- Protein Refseq
- XP_047287032.1; XP_047287033.1
- Function
- Nuclear hormone receptor.
Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1845z | Mouse Anti-ESR2 Recombinant Antibody (clone 35B10) | WB, FC, IF, IHC | Mouse IgG2a |
| MOB-1335MZ | Recombinant Mouse Anti-Human ESR2 Antibody (clone 3F3) | WB | Mouse antibody |
| MRO-0555-CN | Rabbit Anti-ESR2 Recombinant Antibody (clone CBACN-220) | WB | Rabbit IgG |
| ZG-0027C | Mouse Anti-ESR2 Recombinant Antibody (clone PT0318) | IHC-P, IF, WB | Mouse IgG |
| VS3-QX391 | Mouse Anti-ESR2 Recombinant Antibody (clone 555CT18.5.5) | WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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