Rabbit Anti-ESR2 Recombinant Antibody (clone R04-2G5)

CAT#: VS3-XY3350

This is a recombinant rabbit antibody targeting the human ESR2 (Estrogen receptor 2). It has been reported for use in Western Blot and Immunohistochemistry-Paraffin. The recommended dilutions of western blot and Immunohistochemistry-Paraffin is 1/500-1/1000 and 1/50-1/100, respectively.

Gene Expression
Figure 1 IF staining of human cell line SK-MEL-30 Figure 2 Cerebral cortex Figure 3 Colon Figure 4 Liver Figure 5 Testis Figure 6 Lymph node Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70, U-698)

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human ESR2
  • Species Reactivity
  • Human
  • Clone
  • R04-2G5
  • Applications
  • WB, IHC-P
  • Related Disease
  • Ovarian Dysgenesis 8; Thyroid Carcinoma, Familial Medullary

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • WB: 1/500-1/1000
    IHC: 1/50-1/100

Target

  • Alternative Names
  • Erb; ESRB; ODG8; ESTRB; NR3A2; ER-BETA; ESR-BETA
  • Long Name
  • Estrogen receptor 2
  • Cellular Localization
  • Nucleus
  • Post Translation Modifications
  • Phosphorylation at Ser-87 and Ser-105 recruits NCOA1. (Q92731-ESR2_HUMAN)
    Modification sites at PhosphoSitePlus (Q92731)
    Modification sites at neXtProt (NX_Q92731)
  • Function
  • Nuclear hormone receptor.
    Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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COA

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Recommended Dilution Buffer

Secondary Antibody

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