Rabbit Anti-ESR2 Recombinant Antibody (clone R04-2G5) (CAT#: VS3-XY3350)
This is a recombinant rabbit antibody targeting the human ESR2 (Estrogen receptor 2). It has been reported for use in Western Blot and Immunohistochemistry-Paraffin. The recommended dilutions of western blot and Immunohistochemistry-Paraffin is 1/500-1/1000 and 1/50-1/100, respectively.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68406/1984_B8_27_cr5e5cf7eb9f573_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68406/1984_B8_27_cr5e5cf7eb9f573_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166418_B_9_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166418_B_9_5.jpg
Figure 3 Colon
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_3.jpg
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_9_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_9_4.jpg
Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Strong Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/79300/166400_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140009-ESR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140009-ESR2
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human ESR2
- Species Reactivity
- Human
- Clone
- R04-2G5
- Applications
- WB, IHC-P
- Related Disease
- Ovarian Dysgenesis 8; Thyroid Carcinoma, Familial Medullary
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- Erb; ESRB; ODG8; ESTRB; NR3A2; ER-BETA; ESR-BETA
- Gene ID
- 2100
- UniProt ID
- Q92731
- Long Name
- Estrogen receptor 2
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Phosphorylation at Ser-87 and Ser-105 recruits NCOA1. (Q92731-ESR2_HUMAN)
Modification sites at PhosphoSitePlus (Q92731)
Modification sites at neXtProt (NX_Q92731)
- Protein Refseq
- XP_047287032.1; XP_047287033.1
- Function
- Nuclear hormone receptor.
Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1845z | Mouse Anti-ESR2 Recombinant Antibody (clone 35B10) | WB, FC, IF, IHC | Mouse IgG2a |
| MOB-1335MZ | Recombinant Mouse Anti-Human ESR2 Antibody (clone 3F3) | WB | Mouse antibody |
| ZG-0027C | Mouse Anti-ESR2 Recombinant Antibody (clone PT0318) | IHC-P, IF, WB | Mouse IgG |
| VS3-QX391 | Mouse Anti-ESR2 Recombinant Antibody (clone 555CT18.5.5) | WB | Mouse IgG1 |
| VS3-WK1083 | Rabbit Anti-ESR2 Recombinant Antibody (VS3-WK1083) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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