DrugMonitor™ Anti-Etrolizumab Antibody (VS-1224-YC456)
CAT#: VS-1224-YC456
Etrolizumab is a humanized IgG1 kappa monoclonal antibody targeting the β7 subunit of gastrointestinal α4β7 and αEβ7 integrins, under investigation for ulcerative colitis and Crohn's disease treatment. The DrugMonitor™ Anti-Etrolizumab Antibody (VS-1224-YC456) is an anti-drug antibody (ADA) against Etrolizumab. This drug-based antibody is raised in mice immunized with the Etrolizumab. The anti-Etrolizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Etrolizumab in samples.
Specifications
- Host Animal
- Mouse
- Specificity
- Etrolizumab
- Target
- Etrolizumab
- Immunogen
- Etrolizumab
- Type
- Mouse IgG
- Species Reactivity
- Human
- Purity
- >95%
- Purification
- Protein G
- Applications
- ELISA, PK/PD, ADA control
- Format
- Liquid
- Concentration
- Batch-dependent
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
- Generic name
- Etrolizumab
- Related Disease
- ulcerative colitis and Crohn's disease treatment
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