Recombinant Anti-F11 Biparatopic Antibody, Symmetric tandem sdAb
CAT#: VS-0525-YC15
This symmetric anti-Factor XI biparatopic antibody (bpAb) features tandem sdAb arms without light chains (LCs). Designed to disrupt Factor XIa's activity, it may prevent the activation of factor IX (FIX), a key coagulation factor.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line Hep G2
Immunofluorescent staining of human cell line Hep G2 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39808/1663_A5_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000088926-F11
❮
❯
Specifications
- Host Animal 1
- Llama
- Host Animal 2
- Llama
- Specificity
- Factor XI
- Species Reactivity
- Human, Cynomolgus, Rabbit
- Type
- Symmetric tandem sdAb
- Valency
- 2 + 2
- Affinity Constant
- 0.674 nM (Human FXI)
0.152 pM (Cyno FXI)
0.183 nM (Rabbit FXI)
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, Inhib
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Coagulation Factor XI
Target
- Introduction
- This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin or factor XIa to generate active factor XIa protease. Mice lacking the encoded protein display a survival advantage during peritoneal sepsis and resist inflammation and bacterial accumulation upon infection with Listeria.
- Alternative Names
- FXI; PTA; Cf11; 1600027G01Rik
- Gene ID
- 109821
- UniProt ID
- Q91Y47
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| MOB-342-F(E) | Recombinant Anti-human F11 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| MHH-342-F(E) | Recombinant Human Anti-human F11 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| CAT | Product Name | Application | Type |
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| MHH-342-S(P) | Recombinant Human Anti-human F11 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
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| CAT | Product Name | Application | Type |
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| TAB-019WM | Human Anti-F11 Recombinant Antibody (TAB-019WM) | Inhib, ELISA, FC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-020WM | Mouse Anti-F11 Recombinant Antibody (TAB-020WM) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018WM-S(P) | Mouse Anti-F11 Recombinant Antibody; scFv Fragment (TAB-018WM-S(P)) | Inhib, ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-019WM-S(P) | Human Anti-F11 Recombinant Antibody; scFv Fragment (TAB-019WM-S(P)) | Inhib, ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-020WM-S(P) | Mouse Anti-F11 Recombinant Antibody; scFv Fragment (TAB-020WM-S(P)) | WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018WM-F(E) | Mouse Anti-F11 Recombinant Antibody; Fab Fragment (TAB-018WM-F(E)) | Inhib, ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
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| TAB-019WM-F(E) | Human Anti-F11 Recombinant Antibody; Fab Fragment (TAB-019WM-F(E)) | Inhib, ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0377MZ | Recombinant Mouse Anti-Human Factor XI Antibody (clone BIXII-5062) | RIA, WB, ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0539-CN-S(P) | Human Anti-F11 Recombinant Antibody; scFv Fragment (HPAB-0539-CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0539-CN-F(E) | Human Anti-F11 Recombinant Antibody; Fab Fragment (HPAB-0539-CN-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0383-YC-F(E) | Human Anti-F11 Recombinant Antibody; Fab Fragment (HPAB-0383-YC-F(E)) | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0313-YC-S(P) | Human Anti-F11 Recombinant Antibody; scFv Fragment (HPAB-N0313-YC-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
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| HPAB-N0313-YC-F(E) | Human Anti-F11 Recombinant Antibody; Fab Fragment (HPAB-N0313-YC-F(E)) | ELISA | Human Fab |
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