AbPlus™ Anti-FOXO4 Magnetic Beads (CBACN-231) (CAT#: VS-0424-XY106)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-FOXO4 specific antibody (CBACN-231)

• Target
• FOXO4

• Immunogen
• C-terminus of human FOXO4 protein

• Target Species
• Human, Mouse, Rat

• Antibody Clone
• CBACN-231

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene.

• Alternative Names
• Forkhead Box O4; Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated To, 7; Fork Head Domain Transcription Factor AFX1; MLLT7; AFX1; AFX; Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog); Translocated To, 7; Forkhead Box Protein O4

• Gene ID
• 4303

• UniProt ID
• P98177

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