DrugMonitor™ Anti-Fresolimumab Antibody (VS-1224-YC491)

CAT#: VS-1224-YC491

Fresolimumab binds to and inhibits all isoforms of TGF-beta, utilized in trials for treating primary brain tumors, metastatic breast cancer, diffuse systemic sclerosis, malignant pleural mesothelioma, and primary focal segmental glomerulosclerosis. The DrugMonitor™ Anti-Fresolimumab Antibody (VS-1224-YC491) is an anti-drug antibody (ADA) against Fresolimumab. This drug-based antibody is raised in mice immunized with the Fresolimumab. The anti-Fresolimumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Fresolimumab in samples.

Specifications

  • Host Animal
  • Mouse
  • Specificity
  • Fresolimumab
  • Target
  • Fresolimumab
  • Immunogen
  • Fresolimumab
  • Type
  • Mouse IgG
  • Species Reactivity
  • Human
  • Purity
  • >95%
  • Purification
  • Protein G
  • Applications
  • ELISA, PK/PD, ADA control
  • Format
  • Liquid
  • Concentration
  • Batch-dependent
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
  • Generic name
  • Fresolimumab
  • Related Disease
  • primary brain tumors, metastatic breast cancer, diffuse systemic sclerosis, malignant pleural mesothelioma, and primary focal segmental glomerulosclerosis
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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