DrugMonitor™ Anti-Fresolimumab Antibody (VS-1224-YC491) (CAT#: VS-1224-YC491)
Fresolimumab binds to and inhibits all isoforms of TGF-beta, utilized in trials for treating primary brain tumors, metastatic breast cancer, diffuse systemic sclerosis, malignant pleural mesothelioma, and primary focal segmental glomerulosclerosis. The DrugMonitor™ Anti-Fresolimumab Antibody (VS-1224-YC491) is an anti-drug antibody (ADA) against Fresolimumab. This drug-based antibody is raised in mice immunized with the Fresolimumab. The anti-Fresolimumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Fresolimumab in samples.
Specifications
- Host Animal
- Mouse
- Specificity
- Fresolimumab
- Target
- Fresolimumab
- Immunogen
- Fresolimumab
- Type
- Mouse IgG
- Species Reactivity
- Human
- Purity
- >95%
- Purification
- Protein G
- Applications
- ELISA, PK/PD, ADA control
- Format
- Liquid
- Concentration
- Batch-dependent
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
- Generic name
- Fresolimumab
- Related Disease
- primary brain tumors, metastatic breast cancer, diffuse systemic sclerosis, malignant pleural mesothelioma, and primary focal segmental glomerulosclerosis
Downloads
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See other products for "Fresolimumab"
Afuco™ Anti-TGFB1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-140)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to TGF-beta. It is a human monoclonal antibody and an immunomodulator. It is intended for the treatment of idiopathic pulmonary fibrosis (IPF), focal segmental glomerulosclerosis, and cancer (kidney cancer and melanoma).
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For Research Use Only. Not For Clinical Use.
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