Human Anti-FZD5/FZD8/FZD10 Recombinant Antibody (clone F10_A9)
CAT#: VS-0126-FY55
The FZD5/FZD8/FZD10 antibody (VS-0126-FY55) is a specialized Human monoclonal antibody optimized for the precise detection and study of FZD5/FZD8/FZD10. Developed against purified antigens, this antibody exhibits exceptional binding affinity and high specificity for its target. It is validated for use in ELISA and functional assays (FuncS), making it a versatile tool for various experimental protocols. Specifically recognizing Site I of the CRD (Functional site), it ensures accurate results across different research contexts. With demonstrated reactivity in various species, it is suitable for multiple biological models. This high-quality reagent is essential for investigating the functional roles of FZD5/FZD8/FZD10 in Wnt signaling and development.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Antibody Isotype
- IgG1
- Specificity
- Cross-reacts with FZD5, FZD8, FZD10.
- Clone
- F10_A9
- Applications
- ELISA, Functional Assay
Product Property
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Frizzled-5/8/10
- Long Name
- Frizzled Class Receptors 5, 8, and 10
- Function
- A member of the Frizzled receptor family that binds Wnt ligands. It is specifically involved in the Wnt/beta-catenin signaling pathway, which is vital for eye development, yolk sac angiogenesis, and maintaining intestinal stem cell niches.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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