Camelid Anti-GαsRas-Gβγ interface Recombinant Antibody (PABJ-0248)

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Q&As

1. What is the unique target of this antibody?

   A: This antibody targets a specific structural motif: the G-SRAS-G interface. It is an interface-specific antibody, meaning it recognizes the unique conformation formed by this specific amino acid sequence or interaction site, rather than a general protein domain. This makes it invaluable for fine-mapping structural features or protein interactions involving this motif.

2. Is this suitable for structural biology validation?

   A: Yes, interface-specific antibodies like this one are powerful tools for validating structural models. By binding to a specific interface, they can confirm the presence of that conformation in solution. This can complement X-ray crystallography or cryo-EM data by providing biochemical evidence of the structure in a more native-like environment.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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