Rabbit Anti-GEN1 Recombinant Antibody (clone R09-1B8)
CAT#: VS3-FY1727
Clone R09-1B8 is a rabbit recombinant monoclonal antibody that specifically recognizes human GEN1. It cross-reacts with mouse, rat. The specificity of the GEN1 antibody was confirmed by western blot analysis of GEN1 in rat brain, C6, 3T3, Hela lysates.
Tested Data
WB
Figure 1 Anti-GEN1 Antibody (VS3-FY1727) in WB.
The GEN1 expression in rat Brain, C6, 3T3, Hela lysates were detected using the anti-GEN1 by western blot assay.
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Specifications
- Immunogen
- Synthetic peptide of human GEN1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat GEN1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R09-1B8
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 103 kDa, while the observed molecular weight stands at 103 kDa.
- Related Disease
- Xeroderma Pigmentosum, Complementation Group G and Optic Atrophy 6
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- GEN1, Holliday Junction 5' Flap Endonuclease; GEN1, Holliday Junction 5 Flap Endonuclease; Holliday Junction Resolvase; Gen Endonuclease Homolog 1 (Drosophila); Flap Endonuclease GEN Homolog 1; Gen Endonuclease Homolog 1; EC 3.1.-.-; Gen
- Gene ID
- 348654
- UniProt ID
- Q17RS7
- Sequence Similarities
- Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Phosphoprotein
- Protein Refseq
- XP_005262670.1; XP_006712068.1; XP_011531122.1; XP_011531123.1; XP_011531124.1
- Function
- Endonuclease which resolves Holliday junctions (HJs) by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
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