Mouse Anti-GPIIb/IIIa Recombinant Antibody (clone MA-16N7C2) (CAT#: HPAB-0044-YJ)
This product is a recombinant mouse antibody that recognizes human GPIIb/IIIa. Mab MA-16N7C2 can block fibrinogen. In addition, MA-16N7C2, potently inhibits platelet aggregation induced by ADP, thrombin, arachidonic acid, collagen, U46619, adrenaline and platelet-activating factor, whereas ristocetin-induced aggregation was unaffected.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SDS-PAGE
Figure 1 Mouse Anti-GPIIb/IIIa Recombinant Antibody (HPAB-0044-YJ) in SDS-PAGE
SDS-PAGE analysis of HPAB-0044-YJ in non-reduced (Lane 2) and reduced (Lane 1) conditions.
SEC-HPLC
Figure 2 Mouse Anti-GPIIb/IIIa Recombinant Antibody (HPAB-0044-YJ) in HPLC
HPLC analysis of HPAB-0044-YJ shows the purity is>95%.
Specifications
- Immunogen
- BALB/c mice were immunized by intraperitoneal injection of 0.5-3.0×108 gel-filtered platelets from a pool of eight healthy volunteers.
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human GPIIb/IIIa
- Species Reactivity
- Human
- Clone
- MA-16N7C2
- Applications
- ELISA, WB, IP, Inhib, RIA
- Related Disease
- Platelet aggregation
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody MA-16N7C2 has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot, Immunoprecipitation, Inhibition, Radioimmunoassay. It's recommended that the optimal antibody concentration, dilution, incubition time etc. be carefully titrated in specific assays.
Target
- Alternative Names
- ITGA2B/ITGB3; CD41/CD61; MA-16N7C2
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv Antibody Products
Fab Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0044-YJ-S(P) | Mouse Anti-GPIIb/IIIa Recombinant Antibody (clone MA-16N7C2); scFv Fragment | ELISA, WB, IP | Mouse scFv |
| HPAB-2090-FY-S(P) | Human Anti-GPIIb/IIIa Recombinant Antibody (clone PDG8); scFv Fragment | Inhib | Human scFv |
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For Research Use Only. Not For Clinical Use.
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