AbPlus™ Anti-HAT1 Magnetic Beads (VS-0724-YC683) (CAT#: VS-0724-YC683)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-HAT1 specific antibody

• Target
• HAT1

• Immunogen
• Synthetic peptide corresponding to the N-terminus of the human HAT1.

• Target Species
• Human, Mouse, Rat

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]

• Alternative Names
• Histone Acetyltransferase 1; KAT1; Histone Acetyltransferase Type B Catalytic Subunit; EC 2.3.1.48;

• Gene ID
• 8520

• UniProt ID
• O14929

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