Human Anti-HeV RBP Vaccinal Antibody (VS-0625-XY20)
CAT#: VS-0625-XY20
This antibody, specific to the HeV RBP and designed for ELISA use, includes modifications to its Fc segment that produce vaccine-adjuvant effects. The engineered Fc region optimizes interactions with FcγR, thereby boosting antiviral activity through improved neutralization and antibody-dependent cellular responses.
Specifications
- Target
- HeV RBP
- Host Animal
- Human
- Applications
- ELISA
- Specificity
- HeV RBP
- Species Reactivity
- Henipavirus
- Type
- Human IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Epitope
- HeV receptor binding protein (RBP)
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- Hendra virus (HeV), belonging to the Henipavirus genus in the Paramyxoviridae family, are zoonotic pathogens that cause severe viral disease in humans characterized by serious respiratory illness and encephalitis with high mortality. HeV-RBP protein consists of an N-terminal cytoplasmic tail, a single transmembrane helix, a stalk region, and a globular C-terminal receptor binding domain (RBD) with a 6-bladed propeller fold. The two henipavirus surface proteins, RBP and F, mediate viral entry by viral attachment to cells and fusion between the viral envelope and host cell membrane. HeV first attach to host cells by binding to the receptors ephrinB2 or
ephrinB3 using the viral receptor binding protein HeV-RBP.
- Related Disease
- Respiratory disease
- Alternative Names
- Hendra virus receptor binding protein
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Datasheet
MSDS
COA
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Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "HeV RBP"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-XY19 | Human Anti-HeV RBP Vaccinal Antibody (VS-0625-XY19) | ELISA | Human IgG |
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