Mouse Anti-HIV-1 RT Vaccinal Antibody (VS-0625-XY44)
CAT#: VS-0625-XY44
Developed to bind HIV-1 RT, this vaccinal antibody is suitable for ELISA, SPR, and inhibition applications. Fc modification triggers vaccine-like effects and augments antiviral efficacy to combat HIV-1 replication.
Specifications
- Target
- HIV-1 RT
- Host Animal
- Mouse
- Applications
- ELISA; SPR; Inhib
- Specificity
- HIV-1 RT
- Immunogen
- Infectious vaccinia virus recombinant (WRRT) expressing the RT of HIV-1
- Species Reactivity
- HIV-1 (IIIB, Bru and IMS-1)
- Type
- Mouse IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein G purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- During replication of human immunodeficiency virus type 1 (HIV-1), virus-encoded reverse transcriptase (RT) catalyses the conversion of the single-stranded RNA genome to a double-stranded DNA genome. HIV-1 RT functions as a heterodimer, comprising a 66 and a 51 kDa subunit (p66 and p51, respectively). The p66 subunit folds into two distinct domains : a typical polymerase domain and a connected RNase H domain. The second subunit, p51, is a copy of p66 in which the 15 kDa RNase H carboxy-terminal segment has been cleaved by the HIV-1 protease and which lacks a functional nucleic acid-binding cleft. The polymerase domain, p66, consists of four subdomains, which are, by analogy with parts of a right hand, referred to as 'fingers ', 'palm ', ' thumb ' or ' connection '. These subdomains constitute the functional nucleic acid-binding cleft.
- Related Disease
- Acquired Immune Deficiency Syndrome
- Alternative Names
- Human immunodeficiency virus type 1 reverse transcriptase
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-491-F(E) | Recombinant Anti-HIV-1 RT Antibody Fab Fragment | IF, ELISA, FuncS | Fab |
| MHH-491-F(E) | Recombinant Human Anti-HIV-1 RT Antibody Fab Fragment | ELISA, WB, Neut, FuncS | Fab |
| PFBW-070 | Mouse Anti-HIV-1 RT Recombinant Antibody (clone 28); Fab Fragment | WB, FuncS | Mouse Fab |
| FAMAB-0185CQ-F(E) | Mouse Anti-HIV-1 RT Recombinant Antibody (clone MAb 3); Fab Fragment | ELISA, WB, Neut, IF | Mouse Fab |
| FAMAB-0297JF-F(E) | Mouse Anti-HIV-1 RT Recombinant Antibody (clone 7C4); Fab Fragment | ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-491-S(P) | Recombinant Anti-HIV-1 RT Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
| MHH-491-S(P) | Recombinant Human Anti-HIV-1 RT Antibody scFv Fragment | Neut, IF, FuncS | scFv |
| PSBW-070 | Mouse Anti-HIV-1 RT Recombinant Antibody (clone 28); scFv Fragment | WB, FuncS | Mouse scFv |
| FAMAB-0185CQ-S(P) | Mouse Anti-HIV-1 RT Recombinant Antibody (clone MAb 3); scFv Fragment | ELISA, WB, Neut, IF | Mouse scFv |
| FAMAB-0297JF-S(P) | Mouse Anti-HIV-1 RT Recombinant Antibody (clone 7C4); scFv Fragment | ELISA, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-491 | Recombinant Human Anti-HIV-1 RT Antibody | WB, IF, FuncS | IgG |
| MRO-1011CQ | Mouse Anti-HIV-1 RT Recombinant Antibody (clone 39/4.12.2) | ELISA, WB | Mouse IgG1 |
| MRO-1012CQ | Mouse Anti-HIV-1 RT Recombinant Antibody (MRO-1012CQ) | ELISA, IF | Mouse IgG2a |
| MRO-1013CQ | Mouse Anti-HIV-1 RT Recombinant Antibody (MRO-1013CQ) | ELISA, WB | Mouse IgG |
| FAMAB-0185CQ | Mouse Anti-HIV-1 RT Recombinant Antibody (clone MAb 3) | ELISA, WB, Neut, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0829 | PE-B*35:01/HIV-1 RT (VPLDEDFRKY) MHC Tetramer | FCM, IHC | |
| MHC-CN0830 | APC-B*35:01/HIV-1 RT (VPLDEDFRKY) MHC Tetramer | FCM, IHC | |
| MHC-CN0831 | FITC-B*35:01/HIV-1 RT (VPLDEDFRKY) MHC Tetramer | FCM, IHC | |
| MHC-CN0832 | B*35:01/HIV-1 RT (VPLDEDFRKY) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-XY42 | Mouse Anti-HIV-1 RT Vaccinal Antibody (VS-0625-XY42) | ELISA, SPR, Inhib | Mouse IgG |
| VS-0625-XY43 | Mouse Anti-HIV-1 RT Vaccinal Antibody (VS-0625-XY43) | ELISA, SPR, Inhib | Mouse IgG |
| VS-0625-XY45 | Human Anti-HIV-1 RT Vaccinal Antibody (VS-0625-XY45) | ELISA, WB, SPR | Human IgG |
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