Human Anti-HIV gp41 Recombinant Antibody (clone Z13) (CAT#: HPAB-1987-FY)
This product is a recombinant antibody that recognizes HIV gp41. The monoclonal antibody Z13 reacts with the epitope (C-terminus) of HIV gp41.
Specific Inquiry
ELISA
Figure 1 ELISA binding curve of Fab Z13 (κ ) and Fab Z13 (λ 1) against immobilized 2031 peptide. O.D., optical density.
Zwick, M. B., Labrijn, A. F., Wang, M., Spenlehauer, C., Saphire, E. O., Binley, J. M., ... & Parren, P. W. (2001). Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. Journal of virology, 75(22), 10892-10905.
ELISA
Figure 2 Binding by ELISA of Fab b12, IgG 2F5, IgG 4E10, Fab Z13, and IgG KZ52 to various concentrations of HIV-1MN (MN-1000 ) viral particles captured by human anti-HLA MAb L-243.
All MAbs were used at 10 μg/ml. O.D., optical density.
Zwick, M. B., Labrijn, A. F., Wang, M., Spenlehauer, C., Saphire, E. O., Binley, J. M., ... & Parren, P. W. (2001). Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. Journal of virology, 75(22), 10892-10905.
FC
Figure 3 MAb binding to H9 cells infected with HIV-1MN and HIV-1HxB2 as measured by flow cytometry.
H9 cells infected with HIV-1MN were probed with IgG 4E10 (100 μg/ml), Fab Z13 (200 μg/ml), IgG 2F5 (100 μg/ml), IgG b12 (50 μg/ml), IgG 50–69 (10 μg/ml), and Fab ELZ510 (200 μg/ml).
Zwick, M. B., Labrijn, A. F., Wang, M., Spenlehauer, C., Saphire, E. O., Binley, J. M., ... & Parren, P. W. (2001). Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. Journal of virology, 75(22), 10892-10905.
Specifications
- Host Species
- Human
- Type
- Human IgG, κ
- Specificity
- HIV gp41
- Species Reactivity
- HIV
- Clone
- Z13
- Applications
- ELISA, FC
- Related Disease
- HIV
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry.
ELISA: 10 μg/ml.
FC: 200 μg/ml.
Target
- Alternative Names
- Human immunodeficiency virus gp41; HIV gp41
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone Z13"
See other products for "HIV gp41"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-471-F(E) | Recombinant Anti-HIV gp41 Antibody Fab Fragment | RIA, WB, FuncS | Fab |
| PFBL-139 | Human Anti-HIV gp41 (596-606) Recombinant Antibody (clone 7B2); Fab Fragment | Neut, FC, FuncS | Human Fab |
| HPAB-1987-FY-F(E) | Human Anti-HIV gp41 Recombinant Antibody (clone Z13); Fab Fragment | FC, Neut | Human Fab, κ |
| FAMAB-0082WJ-F(E) | Human Anti-HIV gp41 Recombinant Antibody (clone NO.86); Fab Fragment | ELISA, WB | Human Fab |
| FAMAB-0099WJ-F(E) | Human Anti-HIV gp41 Recombinant Antibody (clone 120-16); Fab Fragment | ELISA | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-471-S(P) | Recombinant Anti-HIV gp41 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| HPAB-1987-FY-S(P) | Human Anti-HIV gp41 Recombinant Antibody (clone Z13); scFv Fragment | FC, Neut | Human scFv |
| FAMAB-0082WJ-S(P) | Human Anti-HIV gp41 Recombinant Antibody (clone NO.86); scFv Fragment | ELISA, WB | Human scFv |
| FAMAB-0099WJ-S(P) | Human Anti-HIV gp41 Recombinant Antibody (clone 120-16); scFv Fragment | ELISA | Human scFv |
| FAMAB-0262JF-S(P) | Monkey Anti-HIV gp41 Recombinant Antibody (clone B402); scFv Fragment | FC, ELISA, FuncS | Monkey scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-471 | Recombinant Human Anti-HIV gp41 Antibody | RIA, WB, FuncS | IgG |
| PABL-139 | Human Anti-HIV gp41 (596-606) Recombinant Antibody (clone 7B2) | Neut, FC, FuncS | Human IgG1, κ |
| FAMAB-0082WJ | Human Anti-HIV gp41 Recombinant Antibody (clone NO.86) | ELISA, WB | Human IgG1, κ |
| FAMAB-0099WJ | Human Anti-HIV gp41 Recombinant Antibody (clone 120-16) | ELISA | Human IgG2 |
| FAMAB-0262JF | Monkey Anti-HIV gp41 Recombinant Antibody (clone B402) | WB, ELISA, IHC, FC | Monkey IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-092CT-S(P) | Human Anti-HIV gp41 Recombinant Antibody; scFv Fragment (TAB-092CT-S(P)) | ELISA, Neut | Human scFv |
| TAB-092CT-F(E) | Human Anti-HIV gp41 Recombinant Antibody; Fab Fragment (TAB-092CT-F(E)) | ELISA, Neut | Human Fab |
| PABX-064 | Human Anti-HIV gp41 Recombinant Antibody (clone Z13e1) | WB, Neut, FuncS, ELISA | Human IgG1, λ |
| PABX-064-S (P) | Recombinant Human Anti-gp41 Antibody scFv Fragment (Z13e1) | WB, Neut, FuncS | scFv |
| PABX-064-F (E) | Recombinant Human Anti-gp41 Antibody Fab Fragment (Z13e1) | WB, Neut, FuncS | Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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