Recombinant Anti-HIV1 Rev Biparatopic Antibody, Tandem scFv (Clone rev9 x Clone rev16)
CAT#: VS-0525-YC103
The Recombinant Anti-HIV1 Rev Biparatopic Antibody, Tandem scFv (Clone rev9 x Clone rev16) functions as a biparatopic antibody (bpAb) that engages two distinct HIV1 Rev epitopes. The bpAb's tandem scFv structure incorporates the rev9 scFv, N-terminally linked to the rev16 scFv. The rev9 scFv identifies an epitope spanning amino acids 52-64 and 58-69 of the Rev protein. The rev16 scFv binds to a distinct region encompassing amino acids 75-88, 87-100, and 91-105 of the Rev protein.
Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- HIV Rev
- Species Reactivity
- HIV1
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- rev9
- Clone 2
- rev16
- Epitope 1
- aa 52-64 and 58-69 of rev protein
- Epitope 2
- aa 75-88, 87-100 and 91-105 of rev protein
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, IF, WB
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- HIV-1 Rev protein
Target
- Introduction
- Rev is a transactivating protein that is essential to the regulation of HIV1 protein expression. A nuclear localization signal is encoded in the rev gene, which allows the Rev protein to be localized to the nucleus, where it is involved in the export of unspliced and incompletely spliced mRNAs. In the absence of Rev, mRNAs of the HIV1 late (structural) genes are retained in the nucleus, preventing their translation.
- Alternative Names
- Rev; p19; HIV-1
- Gene ID
- 155908
- UniProt ID
- P04618
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "HIV1 rev"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-028 | Recombinant Anti-HIV1 rev VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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