Recombinant Anti-HIV1 Rev Biparatopic Antibody, Tandem scFv (Clone rev9 x Clone rev16) (CAT#: VS-0525-YC103)

• Host Animal 1
• Human

• Host Animal 2
• Human

• Specificity
• HIV Rev

• Species Reactivity
• HIV1

• Type
• Tandem scFv

• Valency
• 1 + 1

• Clone 1
• rev9

• Clone 2
• rev16

• Epitope 1
• aa 52-64 and 58-69 of rev protein

• Epitope 2
• aa 75-88, 87-100 and 91-105 of rev protein

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA, IF, WB

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• HIV-1 Rev protein

• Introduction
• Rev is a transactivating protein that is essential to the regulation of HIV1 protein expression. A nuclear localization signal is encoded in the rev gene, which allows the Rev protein to be localized to the nucleus, where it is involved in the export of unspliced and incompletely spliced mRNAs. In the absence of Rev, mRNAs of the HIV1 late (structural) genes are retained in the nucleus, preventing their translation.

• Alternative Names
• Rev; p19; HIV-1

• Gene ID
• 155908

• UniProt ID
• P04618

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