Rabbit Anti-HMGN2 Recombinant Antibody (VS13-YC538)
CAT#: VS13-YC538
The Rabbit Anti-HMGN2 Recombinant Antibody is specific for human HMGN2. HMGN2 binds nucleosomal DNA and is linked to active chromatin, potentially maintaining open chromatin for accessible transcription with antimicrobial activities against various pathogens. The anti-HMGN2 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/77364/1634_F6_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18371/623_A12_2_selected.jpg
Normal Tissue
Figure 3 IHC staining of human thyroid gland
Immunohistochemical staining of human thyroid gland shows strong nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18371/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18371/40855_B_9_5.jpg
Normal Tissue
Figure 5 Lung
Alveolar cells type I Staining: High Intensity: Strong Quantity:>75% Alveolar cells type I I Staining: High Intensity: Strong Quantity:>75% Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Macrophages Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18371/40855_A_3_4.jpg
Normal Tissue
Figure 6 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18371/40855_A_8_3.jpg
Normal Tissue
Figure 7 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18371/40855_A_8_4.jpg
Normal Tissue
Figure 8 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18371/40855_A_9_5.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198830-HMGN2
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Specifications
- Immunogen
- Recombinant human HMGN2.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human HMGN2
- Species Reactivity
- Human
- Applications
- WB, IHC-P
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Target
- Alternative Names
- High Mobility Group Nucleosomal Binding Domain 2; High Mobility Group Nucleosome-Binding Domain-Containing Protein 2; High-Mobility Group (Nonhistone Chromosomal) Protein 17; HMG17; High-Mobility Group Nucleosomal Binding Domain 2; Non-Histone Chromosomal Protein HMG-17; Nonhistone Chromosomal Protein HMG-17; High Mobility Group Protein N2;
- Gene ID
- 3151
- UniProt ID
- P05204
- Long Name
- High Mobility Group Nucleosomal Binding Domain 2
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "HMGN2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2477z | Rabbit Anti-HMGN2 Recombinant Antibody (MOB-2477z) | WB, IP, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2477z-F(E) | Recombinant Anti-Human HMGN2 Antibody Fab Fragment | WB, FACS, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2477z-S(P) | Recombinant Anti-Human HMGN2 Antibody scFv Fragment | FC, WB, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3214 | Anti-HMGN2 Immunohistochemistry Kit | IHC |
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