Recombinant Human Anti-HSV Antibody (HX8) (CAT#: HPAB-0026-YJ)
This antibody is a recombinant human antibody that recognizes HSV (Herpes simplex virus). Mab HX8 (HX-8) is an IgA antibody which neutralizes both Herpes simplex virus Type 1 and Type 2, binds to an epitope present on glycoprotein D. This antibody may contribute to the treatment of HSV diseases.
Specific Inquiry
ELISA
Figure 1 HSV-positive sera (n = 260) as determined by both WB and ELISA after preincubation with HSV.
Error bars represent SD.
Hogrefe, W., Su, X., Song, J., Ashley, R., & Kong, L. (2002). Detection of herpes simplex virus type 2-specific immunoglobulin G antibodies in African sera by using recombinant gG2, Western blotting, and gG2 inhibition. Journal of clinical microbiology, 40(10), 3635-3640.
WB
Figure 2 Cosedimentation of HSV with soluble HVEMt.
Secondary Abs were then added, and enhanced chemiluminescence was used to visualize the bands.
Nicola, A. V., De Leon, M. P., Xu, R., Hou, W., Whitbeck, J. C., Krummenacher, C., ... & Cohen, G. H. (1998). Monoclonal antibodies to distinct sites on herpes simplex virus (HSV) glycoprotein D block HSV binding to HVEM. Journal of Virology, 72(5), 3595-3601.
FuncS
Figure 3 Antibody to HSV, by day, after viral vaginal inoculation.
Statistical evaluation was by the two-tailed Student's t test.
Harrison, C. J., Miller, R. L., & Bernstein, D. I. (1994). Posttherapy suppression of genital herpes simplex virus (HSV) recurrences and enhancement of HSV-specific T-cell memory by imiquimod in guinea pigs. Antimicrobial agents and chemotherapy, 38(9), 2059-2064.
Specifications
- Host Species
- Human
- Type
- Human IgA, κ
- Specificity
- Herpes simplex virus (HSV) Type 1 and Type 2
- Species Reactivity
- Herpes simplex virus (HSV) Type 1 and Type 2
- Clone
- HX8
- Applications
- FuncS, WB, ELISA
- Related Disease
- HSV infections or other HSV diseases
Applications
- Application Notes
- The HSV antibody has been reported in applications of Western Blot, Functional Assay, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Human Herpesvirus; HHV; HX-8; HX8
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Recombinant Antibody
Fab Fragment Antibody
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-518 | Recombinant Anti-HSV Antibody | WB, IF, FuncS | IgG |
| MHH-518 | Recombinant Human Anti-HSV Antibody | WB, Dot, FuncS | IgG |
| HPAB-0808-CN | Human Anti-HSV Recombinant Antibody (HPAB-0808-CN) | WB, ELISA, IF | Human IgG |
| HPAB-0809-CN | Human Anti-HSV Recombinant Antibody (HPAB-0809-CN) | WB, ELISA, IF | Human IgG |
| HPAB-J0123-YC | Recombinant Human Anti-HSV Antibody (AC8) | Neut, WB, ELISA, Inhib, IHC | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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