Human Anti-P. falciparum CSP Recombinant Antibody (clone MS-1805)
CAT#: VS-0126-FY37
This is a human monoclonal antibody fragment that specifically targets the Circumsporozoite protein (CSP) of the malaria parasite Plasmodium falciparum (Strain 3D7). This clone recognizes the N-terminal junction peptide, a critical region of the major surface protein on sporozoites.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Antibody Isotype
- IgG
- Species Reactivity
- P. falciparum
- Clone
- MS-1805
Product Property
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- PfCSP, Sporozoite surface protein
- Long Name
- Plasmodium falciparum Circumsporozoite Protein
- Sequence Similarities
- Belongs to the plasmodium circumsporozoite protein family.
- Cellular Localization
- Cell membrane, Cytoplasm, Membrane
- Post Translation Modifications
- During host cell invasion, proteolytically cleaved at the cell membrane in the region I by a papain-like cysteine protease of parasite origin (By similarity).
Cleavage is triggered by the sporozoite contact with highly sulfated heparan sulfate proteoglycans (HSPGs) present on the host hepatocyte cell surface.
- Protein Refseq
- XP_001351122.1
- Function
- CSP, or Content Security Policy, is a security standard that helps prevent the exploitation of cross-site scripting (XSS) attacks by allowing website owners to define where resources like JavaScript can be loaded from. CSP works by specifying the domains from which resources can be loaded, thereby minimizing the risk of XSS attacks by restricting the sources of executable scripts on a website.
The primary function of CSP is to enhance the security of web applications by reducing the potential vulnerabilities that can be exploited by malicious actors. By implementing CSP, website owners can control which external resources can be loaded, reducing the risk of unauthorized code execution and protecting user data.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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